Upon the arrival of his long lost wife, Frankenstein agrees to join her in the ranks of S.H.A.D.E. (the Super Human Advanced Defense Executive), a highly secretive black ops super-agents team making their way to Europe to aid The Resistance. But first, the Creature Commandos will have to stop in Romania to find Nina’s father, the only person who might be able to save Griffith’s life after he is shot by a silver bullet.
When they arrive at their destination, the team finds that it is a village full of many extraordinary and misunderstood creatures being slaughtered by a menace stranger than they are. As time is running out to find Nina’s father, Frankenstein will have to triumph to take on his next mission: as an agent of S.H.A.D.E.